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IL1B — PDGFB
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Worapamorn et al., J Periodontal Res 2002
:
The effect of IL-1 beta on syndecan-1 mRNA synthesis was partially reversed after adding
PDGF-BB and TGF-beta 1, separately or in combination, in the
presence of
IL-1 beta
Eng et al., Microvasc Res 2003
:
Further supporting NF-kappaB regulation of PDGF-B, activation of NF-kappaB by interleukin
(IL)-1beta resulted in increased
PDGF-B transcript levels
Englesbe et al., J Vasc Surg 2004
:
We investigated whether interleukin
(IL)-1beta affects migration in
response to
PDGF-BB
Wondergem et al., Atherosclerosis 2004
:
Compared to cultures exposed to injury alone, radiation
induced significant ( P < 0.05 ) increases in mRNA levels of IL-8 ( 1.35 +/- 0.10-fold increase at 4h ), FGF-2 ( 1.62 +/- 0.10-fold at 4h ; 1.76 +/- 0.33-fold at 24h ) and
IL-1beta ( 2.76 +/- 0.40-fold at 24h ), whereas mRNA levels of TGF-beta1, PDGF-A and
PDGF-B increased about 1.2-fold
Masamune et al., Biochem Pharmacol 2005
:
Ellagic acid inhibited
platelet derived growth factor (PDGF)-BB induced proliferation and migration,
interleukin (IL)-1beta- and tumor necrosis factor (TNF)-alpha induced monocyte chemoattractant protein-1 production, and expression of alpha-smooth muscle actin and collagen genes
Silberstein et al., J Neurochem 1996
:
PDGF B-chain mRNA levels were
increased by TGF-beta 1, TNF-alpha, TNF-alpha/TGF-beta, or
IL-1-beta/TGF-beta 1, whereas PDGF A-chain mRNA levels were not consistently affected by cytokine treatments
Li et al., J Cell Physiol 1997
:
Expression of KGF transcript was down-regulated by EGF, TGF-alpha, and
PDGF-BB , was markedly
up-regulated by
IL-1 beta , and was more pronounced in limbal than in corneal fibroblasts
Walker et al., Biochim Biophys Acta 1998
:
Platelet derived growth factor (PDGF)-BB potently
inhibits secretion of
IL-1beta- and forskolin induced group II PLA2 activity