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IL10 — PARP1
Text-mined interactions from Literome
Aldinucci et al., J Immunol 2007
:
In the same cultures,
PARP-1 inhibitors also
reduced production of IL-12 and
IL-10 ... In the same cultures,
PARP-1 inhibitors also
reduced production of IL-12 and
IL-10
Kang et al., J Immunol 2010
(Genetic Predisposition to Disease...) :
These findings unveil a novel
role of
PARP-1 in the regulation of
IL-10 production in an allele dependent way, which determines individual susceptibility to sepsis induced inflammatory pathology and the immunological sequelae in a physiological process in which clearance of infection induced apoptotic cells by professional phagocytes triggers the cytokine synthesis