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AKT3 — GRB2

Text-mined interactions from Literome

Lim et al., Oncogene 2000 (Breast Neoplasms) : Since Akt can also be activated by heregulin, the effects of Grb2 inhibition on Akt were examined
Tari et al., Oncogene 2002 (Breast Neoplasms) : Liposome incorporated Grb2 antisense oligonucleotides ( L-Grb2 ) and a dominant negative ( DN ) AKT mutant were used to down-regulate Grb2 expression and inhibit Akt activity, respectively
Liu et al., Am J Physiol Endocrinol Metab 2009 (Insulin Resistance) : Suppressing Grb2 expression in C ( 2 ) C ( 12 ) myoblasts enhances insulin stimulated insulin receptor substrate (IRS)-1, tyrosine phosphorylation, and Akt phosphorylation, which is associated with decreased IRS-1 serine phosphorylation at residues 307, 612, and 636/639
Samoylenko et al., Carcinogenesis 2012 (Adenocarcinoma...) : Thereby, Ruk ( l ) /CIN85 led to a more rapid and prolonged epidermal growth factor dependent activation of Src, Akt and ERK1/2 and treatment with the Src inhibitor PP2 and the PI3K inhibitor LY294002 abolished the Ruk ( l ) /CIN85 dependent changes in cell motility