Gene interactions and pathways from curated databases and text-mining

◀ Back to FAS

FAS — TGFB1

Text-mined interactions from Literome

Tanaka et al., J Reprod Immunol 2000 : Flow cytometric analyses demonstrated that TGF-beta1 , IL-1beta, and EGF did not induce Fas expression on the cell surface
Yuen et al., Cancer 2001 (Carcinoma, Hepatocellular...) : The role of transforming growth factor beta 1 ( TGF-beta1 ) in modulating the expression of Fas by CTLs is not known in HCC
Kim et al., Mol Biol Cell 2004 (Carcinoma...) : We showed that TGF-beta 1 induced the expression and activation of Fas and the subsequent caspase-8 mediated Bid cleavage ... Interestingly, expression of dominant negative FADD and treatment with caspase-8 inhibitor efficiently prevented TGF-beta 1-induced apoptosis, whereas the treatment with an activating CH11 or a neutralizing ZB4 anti-Fas antibody, recombinant Fas ligand, or Fas-Fc chimera did not affect activation of Fas and the subsequent induction of apoptosis by TGF-beta 1
Jung et al., Int J Mol Med 2004 (Leukemia...) : Second, TGF-beta1 up-regulated Fas signaling pathway inhibitor cFLIPL to block the pro-caspase-8 cleavage and thus promoted survival of leukaemia/lymphoma cells
Sharma et al., Am J Obstet Gynecol 2009 (Ovarian Neoplasms) : OM-3FAs increased the level of TGF-beta1 , Smad-3, and p21 protein in ovarian cancer cells known to be more sensitive to their inhibitory effect
Tanaka et al., Horm Metab Res 1998 : Flow cytometric analyses showed that TGF-beta 1 did not affect Fas expression on the cell surface
Genestier et al., J Exp Med 1999 : This decrease was associated with inhibition of Fas ( Apo-1/CD95) ligand (FasL ) expression, whereas Fas signaling was not affected by TGF-beta1