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FAS — GLA

Text-mined interactions from Literome

Menendez et al., Int J Oncol 2004 (Breast Neoplasms) : Western blotting studies showed that down-regulation of FAS protein expression tightly correlated with previously observed inhibition of FAS activity, suggesting that ALA-, DHA-, and GLA induced changes in FAS activity resulted from effects at the protein level
Menendez et al., Med Hypotheses 2005 (Breast Neoplasms) : Second, GLA-epoxide inhibits FAS activity, thus resulting in the accumulation of cytosolic malonyl-CoA which, in turn, inhibits carnitine palmitoyl transferase I ( CPT-I ) and prevents FA oxidation