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AHR — EGFR

Text-mined interactions from Literome

Cheon et al., Exp Mol Med 2007 (MAP Kinase Signaling System) : TCDD induced EGFR activation was AhR dependent since co-treatment with alpha-NF prevented it
Randi et al., Toxicol Lett 2008 : Hexachlorobenzene triggers AhR translocation to the nucleus, c-Src activation and EGFR transactivation in rat liver
Sutter et al., Proc Natl Acad Sci U S A 2009 : The total cellular level of p300 protein does not decrease, and overexpression of p300 relieves EGFR mediated repression of transcription, indicating that p300 is a critical target for the repression of the AHR complex by EGFR signaling
Xie et al., Am J Physiol Gastrointest Liver Physiol 2012 (Colonic Neoplasms) : With the use of two human colon cancer cell lines, H508 and SNU-C4, we examined the effects of AhR ligands including 2,3,7,8-tetrachlorodibenzo-p-dioxin ( TCDD ) on cell proliferation and activation of EGFR , ERK1/2, and Src kinases