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ACHE — CASP12
Text-mined interactions from Literome
Toiber et al., PloS one 2008
(Alzheimer Disease) :
In transfected primary brain cultures,
N-AChE-S induced cell death, morphological impairments and
caspase 3 activation
Zhang et al., Frontiers in molecular neuroscience 2012
:
AChE plays a pivotal role in apoptosome formation, and silencing of the AChE gene
prevents caspase-9 activation, with consequent decreased cell viability, nuclear condensation, and poly ( adenosine diphosphate-ribose ) polymerase cleavage
Zhang et al., Int J Biochem Cell Biol 2013
(Disease Models, Animal...) :
In this study, we found that
acetylcholinesterase protein expression increased and
caspase-3 was
activated in PC12 cells treated with 1-methyl-4-phenylpyridinium
Carvajal et al., J Alzheimers Dis 2013
(Alzheimer Disease...) :
Finally, we found that the acute treatment of hippocampal neurons with THH, in the
presence of
Aß-AChE complexes, prevents 4-HNE adduct formation and
caspase-3 activation