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REL — TLR2

Text-mined interactions from Literome

Watanabe et al., Nat Immunol 2004 (Crohn Disease) : Moreover, NOD2 deficiency or the presence of a Crohn disease-like Card15 mutation increased Toll-like receptor 2-mediated activation of NF-kappa B-c-Rel , and T ( H ) 1 responses were enhanced
Knödler et al., Leukemia 2009 : IL-10 was found to downregulate MyD88, IRAK1 ( IL-1 receptor associated kinase ) and tumor necrosis factor receptor associated factor 6, essential adaptor molecules for TLR signaling, and to decrease TLR induced nuclear expression of the nuclear factor-kappaB transcription factors c-Rel and Rel-B as well as interferon regulatory factor (IRF)-3 and IRF-8
Mukhopadhyay et al., Cell Host Microbe 2010 (Meningococcal Infections...) : The NF-?B member c-Rel was essential for TLR- , NOD2-, and NALP3 mediated induction of CD200