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IFNG — MST1
Text-mined interactions from Literome
Matsumoto et al., Vaccine 1999
:
Previously, we constructed a recombinant live BCG ( rBCG ) secreting a 15 kDa C-terminal region of MSP-1 from Plasmodium yoelii ( MSP-1 ( 15 ) ) and succeeded in the induction of more efficient protective immunity against parasite infection than observed with artificial adjuvants ( Matsumoto S, Yukitake H, Kanbara H, Yamada T. Recombinant Mycobacterium bovis bacillus Calmette-Guerin secreting merozoite surface protein 1 (MSP-1) induces protection against rodent malaria parasite infection depending on
MSP-1 stimulated
interferon gamma and parasite-specific antibodies
Genton et al., Vaccine 2003
(Malaria, Falciparum) :
The vaccine induced significant antibody responses to all three antigens but triggered an
IFN-gamma response to
MSP1 only ... At Week 12, the
IFN-gamma response to
MSP1 was substantially higher in the vaccine group where No SP had been given
Avitsur et al., Brain Behav Immun 2006
(Orthomyxoviridae Infections) :
Interestingly,
MSP induced increase in IL-1, TNF-alpha and
IFN-gamma mRNA expression was evident in females, but not in males
Sirima et al., Vaccine 2007
:
After the second dose of MSP3-LSP, there appeared to be a marked increase in the lymphocyte proliferation index and
IFN-gamma in
response to stimulation with
MSP3-LSP
Dent et al., Malaria journal 2009
(Malaria, Falciparum) :
MSP-1 IgG antibodies determined by serology were most consistent over time, followed by
MSP-1 specific T cell
IFN-gamma responses and GIA
Pichyangkul et al., Vaccine 2009
:
Unlike RTS, S,
MSP1 ( 42 ) significantly
reduced AMA1
IFN-gamma and IL-5 responses ... Conversely, AMA1 had no effect on
MSP1 ( 42 ) antibody and
IFN-gamma and IL-5
responses
Matsumoto et al., J Exp Med 1998
(Malaria) :
Recombinant Mycobacterium bovis bacillus Calmette-Guérin secreting merozoite surface protein 1 (MSP1) induces protection against rodent malaria parasite infection depending on
MSP1 stimulated
interferon gamma and parasite-specific antibodies