◀ Back to VPS35
VPS26A — VPS35
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
VPS26A
→
VPS35
(direct_complex)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
VPS35
—
VPS26A
(colocalization, biochemical)
Havugimana et al., Cell 2012
-
IRef Biogrid Interaction:
VPS35
—
VPS26A
(physical association, affinity chromatography technology)
Kristensen et al., Nat Methods 2012
-
MIPS CORUM Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A):
Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) complex (SNX1-SNX2-VPS26A-VPS29-VPS35)
Haft et al., Mol Biol Cell 2000
-
MIPS CORUM VPS35-VPS29-VPS26A complex:
VPS35-VPS29-VPS26A complex complex (VPS26A-VPS29-VPS35)
Haft et al., Mol Biol Cell 2000
-
MIPS CORUM Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A):
Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) complex (SNX1-SNX2-VPS26A-VPS29-VPS35)
Shi et al., Nature structural & molecular biology 2006*
-
IRef Corum Interaction:
Complex of 26 proteins
(association, two hybrid)
Haft et al., Mol Biol Cell 2000
-
IRef Dip Interaction:
Complex of VPS35-VPS35-VPS26A-VPS26A
(anti tag coimmunoprecipitation)
Collins et al., Nature structural & molecular biology 2005*
-
IRef Dip Interaction:
Complex of 16 proteins
(physical association, molecular sieving)
Hierro et al., Nature 2007*
-
IRef Dip Interaction:
VPS35
—
VPS26A
(direct interaction, coimmunoprecipitation)
Shi et al., Nature structural & molecular biology 2006*
-
IRef Dip Interaction:
VPS35
—
VPS26A
(direct interaction, two hybrid)
Shi et al., Nature structural & molecular biology 2006*
-
IRef Dip Interaction:
VPS35
—
VPS26A
(direct interaction, anti tag coimmunoprecipitation)
Hierro et al., Nature 2007*
-
IRef Dip Interaction:
VPS35
—
VPS26A
(direct interaction, pull down)
Hierro et al., Nature 2007*
-
IRef Intact Interaction:
Complex of 15 proteins
(association, tandem affinity purification)
Varjosalo et al., Nat Methods 2013
-
IRef Intact Interaction:
Complex of 400 proteins
(association, cross-linking study)
Humphries et al., Science signaling 2009
Text-mined interactions from Literome
Reddy et al., Mol Biol Cell 2001
:
Vps26p , a component of retromer,
directs the interactions of
Vps35p in endosome-to-Golgi retrieval
Zelazny et al., J Biol Chem 2013
:
Then, by combining live-cell imaging with immunochemical and genetic approaches, we report that
VPS35 alone is able to bind to endosomal membranes and
plays an essential role in
VPS26 and VPS29 membrane recruitment