Gene interactions and pathways from curated databases and text-mining

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HCLS1 — TNF

Text-mined interactions from Literome

Reid et al., Circ Shock 1994 (Neoplasms, Experimental) : We have described a system in which overexpression of the p75-TNFR causes TNF-resistant cells to become TNF-sensitive
Steinshamn et al., Cytokine 1995 (Agranulocytosis...) : In summary, this study shows that endotoxin induced release of sTNFR-p75 is reduced and TNF bioactivity increased in granulocytopenia
Iwamoto et al., Biochem Biophys Res Commun 1994 : TNF individual binding to p75R increased cytotoxic activity when p55R was occupied by htr-9 and a mutein of TNF which significantly lost affinity to p75R