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PDGFB — TGFB1

Text-mined interactions from Literome

Gonias et al., J Biol Chem 2000 : PDGF-BB and NGF-beta blocked the binding of transforming growth factor-beta1 ( TGF-beta1 ) to FP3
Soma et al., Arch Dermatol Res 2002 : We investigated the effect of TGF-beta1 on the mitogenic and chemotactic activities of PDGF A-chain homodimer (PDGF-AA) and B-chain homodimer ( PDGF-BB ) in primary cultures of human skin fibroblasts
Little et al., Diabetes Res Clin Pract 2003 (Diabetic Angiopathies) : Transforming growth factor-beta1 ( 1 ng/ml ) caused a 100 % increase of the PDGF-bb response in both normal and high glucose media
Zhou et al., Endocrinology 2003 : These data indicate that the dual effect of TGF-beta1 is mediated , at least, by up-regulation of PDGF-BB and p15INK4b, respectively
Westhoff et al., Growth Factors 2003 (Fibrosis) : PDGF-BB induces expression of LTBP-1 but not TGF-beta1 in a rat cirrhotic fat storing cell line ... Our data indicate that LTBP-1 but not TGF-beta1 is induced by PDGF-BB and that TGF-beta1 autoinduction does not affect the expression of LTBP-beta1
Breitkopf et al., Growth Factors 2005 (MAP Kinase Signaling System) : We show that PDGF-BB induces TSP-1 and TGF-beta1 via the src kinase pathway whereas TNF-a utilizes the MAPK/Erk pathway
Zhong et al., J Cell Physiol 2006 (Mesothelioma) : PDGF-BB induced , while TGF-beta1 inhibited cell proliferation ... PDGF-BB was a chemoattractant for mesothelial cells, and its effect was increased in the presence of TGF-beta1
Pan et al., Biochem Cell Biol 2007 : The present study aims to assess the effects of PDGF-BB induced overexpression of TGF-beta1 on PCNA in VSMCs ... Our results revealed that PDGF-BB significantly increased the expressions of TGF-beta1 and PCNA, and the increase in PCNA can be partially inhibited by neutralizing anti-TGF-beta1 antibody
Yuan et al., Sichuan Da Xue Xue Bao Yi Xue Ban 2009 (Diabetes Complications...) : The concentration of VEGF increased 2.1-fold, IGF-1 increased 1.95-fold, EGF increased 1.75-fold, PDGF-BB increased 1.89-fold and TGF-beta1 increased 1.67-fold
Risinger et al., Am J Physiol Cell Physiol 2010 : Over time, though PDGF-BB induced increased TGF-beta1 levels, it suppressed TGF-beta2 and TGF-beta3 expression, leading to a net decrease in the total TGF-beta pool, resulting in the upregulation of MMP-2
Pan et al., Zhonghua Xin Xue Guan Bing Za Zhi 2010 : To assess if the modulating effect of platelet derived growth factor (PDGF)-BB on p21 ( WAF1 ) was mediated by upregulating transforming growth factor (TGF)-beta(1) expression in vascular smooth muscle cells ( VSMC )
Ishikawa et al., J Cell Physiol 1990 : TGF-beta 1 enhances mitogenic potency of all three PDGF isoforms and increases receptor binding of both 125I PDGF-AA and 125I PDGF-BB , consistent with the increased expression of the alpha type PDGF receptor
Starksen et al., J Biol Chem 1987 : Previous work in our laboratory has demonstrated that PDGF B chain mRNA expression is stimulated in microvascular endothelial cells by phorbol esters ( PMA ), thrombin, and transforming growth factor-beta ( TGF-beta ) and blocked by agents that elevate cyclic AMP ( cAMP )
Zhang et al., J Dermatol 1995 (Carcinoma, Squamous Cell) : Prostaglandin E1 slightly inhibited PDGF-AB production, transforming growth factor beta 1 promoted PDGF-AB production and interferon-gamma, interleukin-1 alpha, and tumor necrosis factor-alpha failed to exert any influence at all ... Prostaglandin E1 slightly inhibited PDGF-AB production, transforming growth factor beta 1 promoted PDGF-AB production and interferon-gamma, interleukin-1 alpha, and tumor necrosis factor-alpha failed to exert any influence at all
Silberstein et al., J Neurochem 1996 : PDGF B-chain mRNA levels were increased by TGF-beta 1 , TNF-alpha, TNF-alpha/TGF-beta, or IL-1-beta/TGF-beta 1, whereas PDGF A-chain mRNA levels were not consistently affected by cytokine treatments
Rydziel et al., Endocrinology 1996 : TGF beta 1 did not modify the half-life of PDGF-B mRNA in transcriptionally arrested Ob cells and increased the rate of PDGF-B gene transcription in nuclear run-on assays ... In conclusion, normal Ob cells express the PDGF-B gene, and TGF beta 1 induces its transcription, whereas bFGF, IGF-I, and PDGF-BB do not enhance the levels of PDGF-B mRNA
Andresen et al., Curr Eye Res 1998 : PDGF-BB , EGF and TGF-beta 1 stimulated chemotaxis towards a peak value, with a subsequent decline at higher concentrations
Piazuelo et al., Dig Dis Sci 1998 (Stomach Ulcer) : Serum and platelet derived growth factor (PDGF) -BB induced a dramatic increase in both gastric fibroblast proliferation and closure of wounded cell monolayers, whereas these activities were inhibited by both transforming growth factor (TGF) -beta1 and prostaglandin E1