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LOX — TGFB1

Text-mined interactions from Literome

Hong et al., Lab Invest 1999 : This study investigated the regulation by TGF-beta1 of lysyl oxidase and its collagen and elastin substrates in early passage human gingival fibroblasts
Goto et al., Virchows Arch 2005 (Chronic Disease...) : Transforming growth factor-beta1 mediated up-regulation of lysyl oxidase in the kidneys of hereditary nephrotic mouse with chronic renal fibrosis
Colwell et al., Plastic and reconstructive surgery 2006 (Cicatrix...) : The effect of transforming growth factor (TGF)-beta1 on lysyl oxidase expression in fetal fibroblasts was tested
Macauley et al., Wound Repair Regen 1996 : We examined the effect of transforming growth factor-beta1 on the steady-state messenger RNA levels of elastin, alpha2 ( l ) procollagen, and lysyl oxidase ( the enzyme that cross-links both of these structural proteins ) in cell cultures of diploid human fibroblasts established from fetal skin, newborn foreskin, and an adult laryngeal stenotic lesion ... These results show that transforming growth factor-beta1 coordinately increases mRNA levels for the structural extracellular matrix proteins collagen and elastin, as well as for the cross linking enzyme, lysyl oxidase
Atsawasuwan et al., J Biol Chem 2008 : In this study, we investigated the interaction between LOX and transforming growth factor-beta1 ( TGF-beta1 ), a potent growth factor abundant in bone, the effect of LOX on TGF-beta1 signaling, and its potential mechanism
Boak et al., Am J Respir Cell Mol Biol 1994 : Regulation of lysyl oxidase expression in lung fibroblasts by transforming growth factor-beta 1 and prostaglandin E2
Feres-Filho et al., J Biol Chem 1995 : Pre- and post-translational regulation of lysyl oxidase by transforming growth factor-beta 1 in osteoblastic MC3T3-E1 cells ... The goals of this study were to compare the transforming growth factor (TGF)-beta 1 regulation of lysyl oxidase enzyme activity and steady state mRNA levels to changes in COL1A1 mRNA levels in MC3T3-E1 osteoblastic cells ... TGF-beta 1 increased steady state lysyl oxidase and COL1A1 mRNA levels in a dose- and time dependent manner ... Thus, lysyl oxidase regulation by TGF-beta 1 in osteoblastic cell cultures occurs at both pre- and post-translational levels
Roy et al., J Cell Biochem 1996 : Prostaglandin E2, transforming growth factor-beta , and interleukin-1 beta variably regulate the expression of cyclooxygenase 1, cyclooxygenase 2, and lysyl oxidase in IMR90, human embryo lung fibroblasts
Shanley et al., J Vasc Surg 1997 : Transforming growth factor-beta 1 increases lysyl oxidase enzyme activity and mRNA in rat aortic smooth muscle cells ... This investigation was designed to test the hypothesis that transforming growth factor-beta 1 ( TGF-beta 1 ) regulates lysyl oxidase secretion from vascular smooth muscle cells ... The effect of TGF-beta 1 on lysyl oxidase in vascular smooth muscle cells has not been previously defined
Di Donato et al., Nephron 1997 (Fibrosis...) : Lysyl oxidase was expressed by several renal cell lines and in tubular-epithelial cells it was up-regulated in vitro by TGF beta-1 , a recognized fibrogenetic factor in Adriamycin nephropathy
Ren et al., Cancer Res 1998 (Neoplasm Metastasis...) : Using this system, we isolated and sequenced a cDNA fragment that encoded mouse lysyl oxidase (LO) and was induced by transforming growth factor-beta1 in primary tumor but not in metastasis derived cells