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CASP12 — SAA1
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Zhai et al., Neurochem Int 2011
(Calcium Signaling) :
Further studies from Western blot and confocal microscopy experiments showed that the activation of JNK, p38 MAPKs and
caspase-3 during neuron apoptosis triggered by 1 µM colchicine could be obviously
suppressed by
SAA ; on the other hand, an increase in the intracellular free Ca ( 2+ ) by 1 µM colchicine in the cortical neuron was blocked evidently by SAA
Zhai et al., Eur J Pharmacol 2013
:
These results indicate that the activation of JNK, p38 mitogen activated protein kinase ( MAPK ) and
caspase-3 during apoptosis triggered by MPP ( + ) could be
suppressed by
SAA ; on the other hand, an MPP ( + ) -induced increase in the expression of Bax in SH-SY5Y cells was blocked by SAA