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PTTG1 — VEGFA
Text-mined interactions from Literome
McCabe et al., J Clin Endocrinol Metab 2002
(Adenoma...) :
In vitro,
PTTG induced
VEGF , but not KDR, expression in fetal neuronal NT2 cells ( 2.7-fold, P < 0.001, n = 8 ), MCF-7 breast carcinoma cells ( 1.9-fold, P = 0.03, n = 10 ), and choriocarcinoma JEG-3 cells ( P = 0.0002, n = 8 ) ... FGF-2 findings mirrored those of VEGF, although antibody depletion of secreted FGF-2 in the cell medium failed to influence
VEGF up-regulation by
PTTG
Hamid et al., Molecular cancer 2005
(Cell Transformation, Neoplastic...) :
Overexpression of
PTTG1 in HEK293 cells
leads to an increase in the secretion and expression of bFGF,
VEGF and IL-8
Tsai et al., J Clin Endocrinol Metab 2005
(Leiomyoma...) :
Forced expression of
PTTG-1 by transient transfection
stimulates bFGF and
VEGF expression as well as changes the expression pattern of cell cycle proteins