Al-Murrani et al., Biochem J 1999
:
Expression of I2PP2A , an inhibitor of protein phosphatase 2A, induces c-Jun and AP-1 activity
RamÃrez et al., J Cell Biochem 2005
(Carcinoma...) :
Since the inhibition of AP-1 activity following atRA treatment of CA-OV3 cells was abolished in the presence of specific PP2A inhibitors, it is likely that PP2A plays an important role in the atRA induced repression of AP-1
Alberts et al., Mol Cell Biol 1993
:
Consistent with these results, PP2A dephosphorylated c-Jun on negative regulatory sites in vitro, suggesting one possible direct mechanism for the effects of PP2A on AP-1 activity