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MMP2 — PARP1

Text-mined interactions from Literome

Mitra et al., Cancer Res 2008 (Carcinoma, Squamous Cell...) : Rap1GAP up-regulated transcription and secretion of MMP2 and MMP9, as assayed by quantitative reverse transcription-PCR and zymography
Nicolescu et al., Biochem Biophys Res Commun 2009 : As MMP-2 plays a detrimental role in heart injuries resulting from enhanced nitroxidative stress, where PARP and MMP inhibitors are beneficial, we hypothesized that PARP inhibitors may affect MMP-2 activity ... Using substrate degradation assays to determine MMP-2 activity we found that four PARP inhibitors ( 3-AB, PJ-34, 5-AIQ, and EB-47 ) inhibited 64kDa MMP-2 in a concentration dependent manner