Gene interactions and pathways from curated databases and text-mining

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NOS3 — S100A12

Text-mined interactions from Literome

Akiba et al., Am J Physiol Gastrointest Liver Physiol 2001 : Antagonism of vanilloid and CGRP receptors, inhibition of nitric oxide synthase , and sensory deafferentation delayed gel thickening, suggesting that the capsaicin pathway mediated the initial burst of mucus secretion that thickened the gel
Lee et al., Regul Pept 2003 : These results suggest that NTG induced CGRP release is eNOS dependent and tissue- and gender-selective ... Our study revealed a novel eNOS dependent interaction between NO and CGRP , and the possible participation of regulatory peptides in affecting platelet function and possibly cardiovascular protection in females
Wang et al., Am J Physiol Heart Circ Physiol 2004 (Hyperplasia) : Furthermore, CGRP gene transfer increased inducible nitric oxide synthase and p53 but decreased PCNA and Bcl-2 protein levels in balloon injured rat aorta
Harada et al., Thromb Haemost 2005 (Disease Models, Animal...) : In this process, CGRP induced activation of both endothelial nitric oxide synthase and cyclooxygenase-1 might be critically involved
Zheng et al., Am J Physiol Cell Physiol 2010 (Ischemia) : CGRP also induced endothelial nitric oxide synthase (eNOS) phosphorylation in HUVECs at Ser1177 and Ser633 in a time dependent manner, and such effects were abolished by AMPK inhibitor Compound C
Yoshimoto et al., Br J Pharmacol 1998 : 8. These results suggest that in the rat aorta, adrenomedullin and alpha-CGRP increase the endothelial [ Ca2+ ] i, activate nitric oxide synthase and release nitric oxide, without a direct inhibitory action on smooth muscle