Zhang et al., J Biol Chem 2007
:
Increased iNOS activity was dependent on B1R activation of the MAPK ERK
Brovkovych et al., J Cell Mol Med 2011
(MAP Kinase Signaling System) :
B1R dependent iNOS activation was also inhibited by Src family kinase inhibitor PP2 and trans-fection with dominant negative Src
Kuhr et al., FASEB J 2010
(Inflammation) :
We report here that B1R mediated iNOS activation was significantly inhibited by knockdown of beta-arrestin 2 with siRNA in cytokine treated HLMVECs or HEK293 cells transfected with iNOS and B1R