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BCL6 — NGF
Text-mined interactions from Literome
Bui et al., J Cell Biol 2001
:
We investigated the
effect of
NGF on the expression of
Bcl-xL , an anti-apoptotic Bcl-2 family protein ...
NGF induced NFkappaB activity and
Bcl-xL expression were inhibited in cells overexpressing the NFkappaB inhibitor, IkappaBalpha
Bui et al., J Neurochem 2002
(Pheochromocytoma) :
We have previously shown that
nerve growth factor (NGF) induced activation of nuclear factor-kappaB
increased neuronal expression of
Bcl-xL , an anti-apoptotic Bcl-2 family protein ... Treatment of hippocampal neurones with the blocking anti-p75 antibody inhibited constitutive and
NGF induced
Bcl-xL expression, activation of Akt, and blocked the protective effect of NGF against excitotoxic and apoptotic injury