Gene interactions and pathways from curated databases and text-mining

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ADAM10 — MYLIP

Text-mined interactions from Literome

Augustin et al., BMC medical genetics 2012 (Alzheimer Disease...) : ADAM10 expression in the reporter assay was reduced by miR-1306 ( 28 % ), miR-103 ( 45 % ) and miR-107 ( 52 % )
Cheng et al., J Biol Chem 2013 (Alzheimer Disease) : In this study, we demonstrated that overexpression of miR-144 , which was previously reported to be increased in elderly primate brains and AD patients, significantly decreased activity of the luciferase reporter containing the ADAM10 3'-untranslated region ( 3'-UTR ) and suppressed the ADAM10 protein level, whereas the miR-144 inhibitor led to an increase of the luciferase activity ... In addition, we found that miR-451 , a miRNA processed from a single gene locus with miR-144, is also involved in the regulation of ADAM10 expression