Nakayama et al., J Exp Med 2000
(Carcinoma, Squamous Cell) :
Although freshly isolated PBMCs expressed no detectable level of TWEAK on their surfaces, a remarkable TWEAK expression was rapidly observed on monocytes upon stimulation with interferon (IFN)-gamma but not with IFN-alpha or lipopolysaccharide
Maecker et al., Cell 2005
(Hypersensitivity) :
Thus, TWEAK suppresses production of IFN-gamma and IL-12, curtailing the innate response and its transition to adaptive TH1 immunity