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CCL4 — IFNG

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CCL4 → IFNG (decreases) Wang et al., J Immunol 1999*
  Evidence: IL-4, IL-10, IFN-gamma and IL-18 strongly inhibited MIP-1beta production.
• OpenBEL Selventa BEL large corpus: CCL4 → IFNG (increases) D'Aversa et al., Am J Pathol 2002*
  Evidence: Treatment of cells with CD40L and IFN-gamma induced both protein and mRNA expression of MIP-1beta. CD40L induced MIP-1beta expression was potentiated by IFN-gamma

Text-mined interactions from Literome

Wang et al., J Immunol 1999 : IL-4, IL-10, IFN-gamma , and IL-18 primarily inhibited MIP-1beta secretion and also weakly suppressed MIP-1alpha secretion
Majka et al., J Clin Invest 1999 : We found that human CD34 ( + ) cells and CD34 ( + ) KIT ( + ) cells, which are enriched in myeloid progenitor cells, expressed and secreted the CCR5 ligands RANTES, MIP-1alpha, and MIP-1beta and that IFN-gamma stimulated expression of these chemokines
Hedman et al., Clin Exp Immunol 2008 (Diabetes Mellitus, Type 1) : The percentages of CD4 ( + ) cells expressing CXC chemokine receptor 3 (CXCR3), CXCR6 and CCR5, and the secretion of interferon-gamma induced protein-10, monocyte chemoattractant protein-1, macrophage inflammatory protein (MIP)-1alpha and MIP-1beta was lower among diabetics
Machado et al., Microbes Infect 2008 : Interestingly, T. cruzi infected NOS2-deficient CMs produced significantly higher levels of CCL2, CCL4 , CCL5 and CXL2 in the presence of IFN-gamma and TNF