Gene interactions and pathways from curated databases and text-mining

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GDF15 — SP1

Text-mined interactions from Literome

Shim et al., J Biol Chem 2005 (Inflammation...) : NAG-1 ( nonsteroidal anti-inflammatory drug activated gene ), a member of the transforming growth factor beta superfamily, is involved in cellular processes such as inflammation, apoptosis/survival, and tumorigenesis and is regulated by p53, Sp1 , and Egr-1
Yoshioka et al., J Biol Chem 2008 (Glioblastoma) : Reporter gene assays, specific inhibition by small interfering RNA transfections, and chromatin immunoprecipitation assays indicate that Egr-1 and Sp-1 mediate TSA induced NAG-1 expression