Gene interactions and pathways from curated databases and text-mining

◀ Back to CDKN1A

CDKN1A — WT1

Text-mined interactions from Literome

Wang et al., J Biol Chem 2001 : Retrovirally driven expression of either the CBP fragment or of E1A in human hematopoietic cells suppresses the induction by WT1 of its endogenous target gene, p21 ( Cip1 )
Loeb et al., J Biol Chem 2002 : Because induction of WT1 leads indirectly to increased p21 expression in osteosarcoma cells, we investigated the possibility that other genes involved in the G ( 1 ) /S phase transition might also be WT1 targets
Noh et al., Biochem Biophys Res Commun 2004 (MAP Kinase Signaling System) : HBx WT1 and WT2, but not SA2, repressed transcription from the p21 ( WAF1/Cip1 ) promoter
Ozpolat et al., Mol Cancer Res 2007 (Acute Disease...) : Knockdown of PDCD4 by RNA interference ( siRNA ) inhibited ATRA induced granulocytic differentiation and reduced expression of key proteins known to be regulated by ATRA, including p27 ( Kip1 ) and DAP5/p97, and induced c-myc and Wilms' tumor 1 , but did not alter expression of c-jun, p21 ( Waf1/Cip1 ), and tissue transglutaminase ( TG2 )
Englert et al., Cancer Res 1997 (Osteosarcoma) : WT1 mediated induction of p21 is independent of p53, another tumor suppressor gene known to regulate p21 expression