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CDKN1A — SOAT1
Text-mined interactions from Literome
Kawamata et al., Int J Oncol 1999
(Urinary Bladder Neoplasms) :
Reportedly EGF activates
STAT ,
induces the expression of
p21waf1 , and subsequently inhibits the growth of several types of cancer cells ... These results suggest that i ) EGF inhibits the growth of T24 cells via
induction of
p21waf1 mediated by
STAT , and ii ) the balance between the STAT induced p21waf1 and MAPK activities regulates the growth of human bladder cells after EGF treatment
Huang et al., J Biol Chem 2000
:
The increased expression of
p21 ( waf/cip1 ) by thrombin was p53 independent,
STAT1 dependent , and protein synthesis independent
Chen et al., Cancer Res 2000
(Muscle Neoplasms...) :
We further studied the effects of SIE-1 hypermethylation on
p21WAF1 induction by
STAT activation
Barré et al., J Biol Chem 2003
(Cell Transformation, Neoplastic) :
In this study, we show that upon IL-6 stimulation of glioblastoma cells,
STAT3 does not
activate the expression of the
p21 ( waf1 ) gene, whereas the expression of the myc gene remains unaltered
Dubourdeau et al., Eur Cytokine Netw 2008
:
Opposite
roles of
STAT and PPARgamma in the induction of
p21WAF1 expression by IL-13 in human peripheral blood monocytes