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APOB — CCR2

Text-mined interactions from Literome

Han et al., J Lipid Res 1999 (Hypercholesterolemia) : Elevated levels of high density lipoprotein ( HDL ) blunted and even reverted the effects of LDL on CCR2 expression, both in vivo and in vitro
Han et al., J Clin Invest 2000 (Arteriosclerosis) : Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator activated receptor gamma ... In contrast, oxidized LDL ( OxLDL ), which is mainly formed in the aortic intima, reduces CCR2 expression, promotes monocyte retention, and may cause pathological accumulation of monocytes in the vessel wall
Han et al., J Lipid Res 2003 : In a previous study, we showed that LDL induces the expression of CCR2 in monocytes
Isoda et al., Atherosclerosis 2008 : Glycated LDL increases monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1 mediated chemotaxis ... These data show that AGE-LDL can increase CCR2 expression in macrophages and stimulate the chemotactic response elicited by MCP-1