Rhoads et al., Am J Physiol Gastrointest Liver Physiol 2006
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We conclude that mTOR/p70 ( s6k ) signaling is essential to intestinal cell migration, is activated by ARG , involves both nuclear and cytoplasmic events, and may play a role in intestinal repair
Rhoads et al., J Nutr 2008
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To investigate the mechanism of response to Arg, we used the rat crypt cell line cdx2 transformed IEC-6 cells ( cdx2-IEC ) and measured cell migration, immunocytochemical analysis of p70 ( s6k ) activation in response to Arg , and production of nitric oxide ( NO )