Manolopoulos et al., Mol Psychiatry 2010
(Alzheimer Disease...) :
Wnt inhibition may also result in a sustained activation of FoxO proteins with induction of apoptosis and neuronal loss, thereby completing a vicious circle from oxidative stress, InsRes and hyperglycaemia back to the formation of ROS and consecutive neurodegeneration
Dieudonné et al., J Bone Miner Res 2012
(Bone Neoplasms...) :
Doxorubicin modulated Foxo3a binding on syndecan-2 gene promoter and induced Foxo dependent inhibition of Wnt/TCF activity