Gene interactions and pathways from curated databases and text-mining

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CDC23 — PLK4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

  • STRING interaction: PLK4 — CDC23 (interaction, mapped from grid reactome kegg_pathways mint intact)
  • STRING interaction: CDC23 — PLK4 (interaction, mapped from grid reactome kegg_pathways mint intact)

Text-mined interactions from Literome

Liu et al., Proc Natl Acad Sci U S A 2002 : Plks have been reported to mediate multiple mitotic processes, including bipolar spindle formation, activation of Cdc25C, actin ring formation, centrosome maturation, and activation of the anaphase promoting complex
Kotani et al., Mol Cell 1998 : PKA and MPF activated polo-like kinase regulate anaphase promoting complex activity and mitosis progression