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MAPK12 — NRAS
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Giehl et al., Oncogene 2000
(Pancreatic Neoplasms) :
Stimulation of cells with epidermal growth factor (EGF) or fetal calf serum ( FCS ) resulted in
activation of
N-Ras , but not K-Ras, as well as activation of c-Raf, MEK-1, and p42
MAPK
Whitwam et al., Oncogene 2007
(Cell Transformation, Neoplastic...) :
Although both
NRAS and KRAS
activate mitogen activated protein kinase signaling, only NRAS enhances MYC activity in these cells
Hamilton et al., Oncogene 1998
:
Ha-ras and
N-ras regulate
MAPK activity by distinct mechanisms in vivo