Ohteki et al., J Immunol 2001
:
Mice lacking IFN-regulatory factor (IRF)-1 have reduced numbers of mature CD8+ T cells within the thymus and peripheral lymphoid organs, suggesting a critical role of IRF-1 in CD8 ( + ) T cell differentiation
Brien et al., PLoS Pathog 2011
(West Nile Fever) :
IRF-1 also had an independent and paradoxical effect on CD8 ( + ) T cell expansion