Gene interactions and pathways from curated databases and text-mining

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INS — ZFP36

Text-mined interactions from Literome

Cao et al., Obesity (Silver Spring) 2008 (Disease Models, Animal...) : Little is known about the expression and insulin regulation of TTP and related genes in adipocytes ... Insulin at 10 and 100 nmol/l increased Ttp mRNA levels by five- to sevenfold, but decreased those of Zfp36l3 by 40 % in adipocytes after a 30-min treatment ... Immunoblotting showed that insulin induced TTP but did not affect ZFP36L1 protein levels in adipocytes
Cao et al., J Nutr 2008 (Inflammation) : TTP expression is reduced in fats of obese people with metabolic syndrome and brains of suicide victims and is induced by insulin and cinnamon polyphenol extract (CPE) in adipocytes, by lipopolysaccharide (LPS) in macrophages, and by green tea polyphenol extract in rats
Lai et al., J Biol Chem 1990 : Insulin induction of TTP mRNA accumulation was prevented by actinomycin D and superinduced by cycloheximide
Corps et al., FEBS Lett 1995 : Insulin and insulin-like growth factor I stimulate expression of the primary response gene cMG1/TIS11b by a wortmannin-sensitive pathway in RIE-1 cells ... Insulin/IGF-I did not affect the expression of the cMG1 related genes TIS11 and TIS11d , whereas epidermal growth factor, angiotensin II or 12-O-tetradecanoyl phorbol-13-acetate stimulated the expression of all three genes