Gene interactions and pathways from curated databases and text-mining

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INS — UCP3

Text-mined interactions from Literome

Pedersen et al., Biochem Biophys Res Commun 2001 : Insulin and contraction directly stimulate UCP2 and UCP3 mRNA expression in rat skeletal muscle in vitro ... In conclusion, UCP2 and UCP3 mRNA expression in skeletal muscle are stimulated rapidly by insulin and contraction in vitro, thus the stimulation is direct and not caused by changes in other hormones or metabolites
Gustafsson et al., Biochem Biophys Res Commun 2001 (Diabetes Mellitus, Type 2...) : In this study the expression of uncoupling protein 3 (UCP3) and its regulation by insulin-like growth factor 1 (IGF-I) and insulin in human neuroblastoma SH-SY5Y cells were characterized
Gustafsson et al., J Neurosci Res 2004 (Diabetic Neuropathies...) : We have previously shown that UCP3 expression is positively regulated by insulin-like growth factor-1 (IGF-1)
Li et al., PloS one 2008 : Increased expression of UCP-2 and decreased expression of UCP-3 in humans with chronic hyperglycemia may contribute to impaired glucose stimulated insulin secretion
Qiao et al., Biol Trace Elem Res 2009 : At the molecular level, insulin significantly increased the mRNA levels of insulin receptor (IR), glucose transporter 4 (GLUT4), glycogen synthase ( GS ), and uncoupling protein-3 (UCP3) , and these impacts can be enhanced by the addition of chromium, especially in the form of CrSP