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INS — SYTL4
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Torii et al., Mol Cell Biol 2002
:
Overexpression of
granuphilin significantly
enhances basal
insulin secretion but profoundly inhibits high K ( + ) -induced insulin secretion ... The
effect of
granuphilin on
insulin secretion was impaired by its mutation that disrupts the binding to either Rab27a or syntaxin 1a
Kato et al., Cell Metab 2006
(Diabetes Mellitus, Experimental) :
Granuphilin is activated by SREBP-1c and
involved in impaired
insulin secretion in diabetic mice