Sumitani et al., Endocrinology 2002
:
These results suggest that insulin regulates myogenic differentiation chiefly at the level of myogenin gene transcription via PI3K and mTOR
Rochat et al., Mol Biol Cell 2004
(Hypertrophy) :
Similarly to the effect of GSK-3 inhibitors with insulin, coculturing C2 reserve cells with Wnt1 expressing fibroblasts enhanced insulin stimulated induction of MyoD and myogenin in reserve cells
Theil et al., Meat Sci 2006
:
Insulin stimulated differentiation as indicated by elevated creatine kinase activity but did not affect myogenin transcription