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INS — MCAT

Text-mined interactions from Literome

Chenal et al., Eur J Neurosci 2008 : Insulin and IGF-1 enhance the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin pathway ... In parallel, it was observed that LY294002 and rapamycin almost completely blocked the effects of insulin and IGF-1 on MCT2 protein expression, whereas PD98059 and SB202190 ( a p38K inhibitor ) had no effect on insulin induced MCT2 expression and only a slight effect on IGF-1 induced MCT2 expression
Pullen et al., Diabetes 2012 (Hyperinsulinism) : MCT1 expression caused isolated islets to secrete insulin in response to pyruvate, without affecting glucose stimulated insulin secretion
Berelowitz et al., Endocrinology 1980 (Carcinoma...) : The results indicate that SRIF-LI is produced in excessive quantities by a transplantable rat MCT and impairs the secretion of GH and insulin