Salvador et al., J Neurosci Res 2005
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In aged animals, PLD activity was not modified by the presence of insulin plus vanadate, PAP2 was inhibited, and DAGK was stimulated by the hormone
Zulian et al., J Neurosci Res 2006
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The mechanism by which insulin increases diacylglycerol kinase (DAGK) activity has been studied in cerebral cortex ( CC ) synaptosomes from adult ( 3-4 months of age ) rats ... The purpose of this study was to identify the role of phospholipases C and D ( PLC and PLD ) in DAGK activation by insulin ... PIP2-PLC activation may contribute at least partly to the insulin effect on DAGK activity
Zulian et al., Neurochem Int 2011
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DAGK activity over SAG was more highly stimulated by insulin in CC and Hp synaptosomes of aged rats with respect to adult rats