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AGTR2 — INS

Text-mined interactions from Literome

Okazaki et al., Exp Anim 2002 (Albuminuria...) : In both diabetic mice, especially KK-Ay mice, plasma insulin levels markedly increased at 2 to 4 months of age, and the urinary glucose and microalbumin levels and albumin-to-creatinine ratios increased dependent on age
Hussain et al., Clin Exp Hypertens 2003 (Hyperinsulinism...) : Whole animal and in vitro studies indicate that higher plasma insulin level, generally associated with obesity, is responsible for the up-regulation of both AT1 and AT2 receptors in the kidney
Shimizu et al., J Endocrinol Invest 1991 : At 2 h later, rhIL-1b significantly suppressed insulin release by pentobarbital injection in both intact and ADX rats
Diamond-Stanic et al., Biochem Biophys Res Commun 2011 (Insulin Resistance) : We therefore studied the effects of a low-level in vitro oxidant stress ( 30-40 µM H2O2 ) on basal and insulin stimulated ( 5 mU/ml ) glucose transport activity and insulin signaling at 2 , 4, and 6 h in isolated rat soleus muscle ... In the presence of insulin , H2O2 decreased total protein expression of IRS-1 at 6 h and IRS-2 at 4 and 6 h. Phosphorylation of p38 MAPK Thr180/Tyr182 was transiently increased by H2O2 in the presence and absence of insulin at 2 and 4 h, but not at 6 h. Selective inhibition of p38 MAPK with A304000 partially rescued the H2O2 induced reduction in insulin stimulated glucose transport activity
Yoshiji et al., Curr Cancer Drug Targets 2011 (Carcinoma, Hepatocellular...) : It is well known that AT-II plays an important role in the insulin resistance (IR) , and IR is reportedly involved in the progression of HCC
Liu et al., J Neurosci Methods 2012 : Insulin ( 0.5 and 1 U/kg ) led to a significant increase of insulin in both plasma and CSF at 2 h after intraperitoneal administration and decreased blood glucose for at least 2h
Nizielski et al., Physiol Behav 1986 : However, insulin ( 50 and 100 Units/kg ) resulted in significant increases in food consumption at 2 and 4 hours ( p less than 0.01 and 0.05, respectively ) when administered while the animals were hypophagic
Lebrun et al., Metabolism 1985 : Methylamine, at 2 or 5 mmol/L, partially inhibited insulin release but failed to affect the continuous electrical activity in islets exposed throughout to 22.2 mmol/L glucose
Pierluissi et al., Diabetologia 1981 : Insulin release in the presence of glucose at 2 or 12 mmol/l was not affected by DAMME ( 8.3 X 10 ( -8 ) mol/l )
Freund et al., Cancer Res 1994 (Burkitt Lymphoma...) : In the 8226 cells, insulin increased lactate production 4 +/- 4 and 36 +/- 15 % at 2 and 200 nM, respectively
Kambayashi et al., Eur J Biochem 1996 (Hyperinsulinism...) : The insulin induced expression of AT2 was detected in the aorta of genetically obese ( fa/fa ) Zucker rats, which reportedly have approximately tenfold-higher plasma concentrations of insulin than their lean littermates
Saward et al., Mol Cell Endocrinol 1996 : These data suggest the AT2 receptor, which mediates the growth effects of angiotensin II in A10 cells, may be the critical target for the effect of insulin
Becker et al., Kidney Int 1997 : Effect of glucose, pyruvate, and insulin on type 1 angiotensin II receptor expression in SV40 immortalized rabbit proximal tubule epithelial cells