Wahl et al., J Am Soc Nephrol 2002
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Interestingly, interleukin-2 production by T cell hybridomas after antigen presentation by TEC was enhanced by blocking antibodies to B7RP-1 and ICOS Ogata et al., Int Immunol 2013
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We also showed that pDC derived TNF-a induced ICOS-L expression on pDCs in an autocrine manner and that IL-6 promoted ICOS expression on T-cells, contributing to the ICOS/ICOS-L mediated T-cell response