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IL10 — NGF
Text-mined interactions from Literome
Bulló et al., Am J Physiol Endocrinol Metab 2005
:
Although interleukin (IL)-1beta,
IL-10 , and IL-18 each
induced a small decrease in
NGF mRNA level in 3T3-L1 adipocytes, there was no significant effect of these cytokines on NGF secretion
Jelaso et al., Int J Dev Neurosci 2005
:
In the mammalian nervous system, the cytokine,
interleukin-1beta (IL-1beta)
induces expression of
NGF
Micera et al., Molecular vision 2009
(Conjunctivitis, Allergic) :
NGF triggered a dose-response release of
IL-10 in VKC-ECs conditioned media, an effect not detected for IL-4, IL-12 p40, and IFN-gamma
Marianecci et al., J Control Release 2010
:
The treatment of HLF cells with BDP loaded non-ionic surfactant vesicles determined a noticeable increase of the drug anti-inflammatory activity by reducing the secretion of both constitutive and
interleukin-1ß stimulated
nerve growth factor ( as inflammatory index ) of 68 % and 85 %, respectively
Varilek et al., Am J Physiol 1995
:
Caco-2 monolayers primarily secreted
NGF from the basolateral compartment, and
interleukin-1 enhanced its secretion
Pshenichkin et al., J Neurochem 1994
:
Transcriptional and posttranscriptional mechanisms involved in the
interleukin-1 , steroid, and protein kinase C
regulation of
nerve growth factor in cortical astrocytes
Brodie et al., FEBS Lett 1996
:
We have examined the
effect of the Th2 derived cytokine
IL-10 and the Th1 derived cytokines Il-2 and IFN-gamma on the secretion of
NGF by mouse astrocytes ...
IL-10 induced a dose dependent increase in
NGF secretion which was blocked by anti-IL-10 antibody ... Moreover, INF-gamma completely inhibited the increase in
NGF secretion
induced by
IL-10 whereas it had no effect on the induction of NGF by TNF-alpha