◀ Back to CTGF

BMP7 — CTGF

Text-mined interactions from Literome

Abreu et al., Nat Cell Biol 2002 : These results show that CTGF inhibits BMP and activates TGF-beta signals by direct binding in the extracellular space
Mou et al., Proc Natl Acad Sci U S A 2006 : Edar activation also induces connective tissue growth factor , an inhibitor of BMP signaling, allowing BMP action only at a distance from their site of synthesis
Nguyen et al., J Am Soc Nephrol 2008 (Diabetes Mellitus, Experimental...) : CTGF inhibits BMP-7 signaling in diabetic nephropathy ... In cultured renal glomerular and tubulointerstitial cells, CTGF diminished BMP-7 signaling activity, evidenced by lower levels of pSmad1/5, Id1 mRNA, and BMP-responsive element-luciferase activity
Fuchshofer et al., Exp Eye Res 2009 : Following combined BMP7/TGF-beta2 treatment, the antagonizing effect of BMP7 on TGF-beta2 induced CTGF expression was abolished
Xu et al., Zhonghua Yi Xue Za Zhi 2009 : To investigate the effects of bone morphogenic protein (BMP)-7 upon epithelial-to-mesenchymal transition ( EMT ) and the expression of connective tissue growth factor (CTGF) in human renal proximal tubular epithelial cells ( HK-2 ) induced by transforming growth factor-beta1, ( TGF-beta1 ) and to explore the possible mechanisms of BMP-7 for the inhibition and reversal of renal interstitial fibrosis
Meurer et al., Eur J Cell Biol 2012 : However, although siRNA mediated knock down of Alk2/3 or Smad1/5 counteracts the BMP-7 effect on basal CTGF expression there was no consistent reversion of the observed BMP-7 effect on TGF-ß1 mediated CTGF expression