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CHUK — IFNG

Text-mined interactions from Literome

Chae et al., Immunopharmacol Immunotoxicol 2004 : TNF-alpha plus IFN-gamma can induce extracellular signal regulated kinase ( ERK ), IKK , IkappaB degradation and NF-kappaB activation
Shiao et al., Br J Pharmacol 2005 : Treatment with 50 microM of falcarindiol for 60 min diminished the LPS/IFN-gamma mediated activation of IkappaB kinase-alpha (IKK-alpha) and IKK-beta by 28.2 and 29.7 %, respectively
Kårehed et al., Mol Immunol 2007 : We further show that IFN-gamma induction of FcgammaRI upregulation is dependent on the NFkappaB pathway, as evidenced by inhibition of NFkappaB using a phosphorylation defective IkappaBalpha ( S32A/S36A ) mutant, or inhibiting the IkappaB-kinase (IKK) by treatment with BMS345541
Hong et al., J Surg Res 2010 : Immunocomplex assay involving GST-IKK revealed that cAMP inhibited IL-1beta plus IFNgamma induced IKK activity
Shultz et al., J Interferon Cytokine Res 2009 : In response to IFN-gamma , inhibitor of NF-kappaB (IkappaB) kinase beta ( IKK-beta ) is required to activate both newly synthesized IRF1 and the p65 subunit of NF-kappaB, which contributes to ip-10 expression by binding to kappaB sites in the ip-10 promoter, with little or no activation of classical NF-kappaB