Gene interactions and pathways from curated databases and text-mining

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PSMG1 — TP53

Text-mined interactions from Literome

Ciani et al., Brain Res Mol Brain Res 1999 (Brain Ischemia) : Induction of the PAC1-R ( PACAP-type I receptor ) gene by p53 and Zac ... We report here that p53 and Zac induce expression of the PAC1-R gene
Yin et al., Nature 2003 : Here we show that during apoptosis, p53 activates transcription of PAC1 by binding to a palindromic site in the PAC1 promoter ... We conclude that, under specific stress conditions, p53 regulates transcription of PAC1 through a new p53 binding site, and that PAC1 is necessary and sufficient for p53 mediated apoptosis