Gene interactions and pathways from curated databases and text-mining

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IGFBP7 — TP53

Text-mined interactions from Literome

Suzuki et al., Carcinogenesis 2010 (Adenocarcinoma...) : Luciferase and chromatin immunoprecipitation assays in unmethylated cells revealed that p53 induces expression of IGFBP7 upon binding to a p53 response element within intron 1 of the gene ... Treating methylated CRC cell lines with 5-aza-2'-deoxycytidine restored p53 induced IGFBP7 expression
Kim et al., Nucleic Acids Res 2012 : SET/TAF-Iß interacted with p53 and repressed transcription of p53 target genes ... Our findings provide new insights into the regulation of stress induced p53 activation by HAT inhibiting histone chaperone SET/TAF-Iß