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DDX58 — TP53

Text-mined interactions from Literome

Hsu et al., FEBS Lett 2012 : Transfection studies revealed that the RIG1 promoter activity was greatly enhanced by wild type but not mutated p53 protein
Sun et al., Biochim Biophys Acta 2013 (Breast Neoplasms) : Thus, DDX3 associates with p53, increases p53 accumulation, and positively regulates camptothecin induced apoptotic signaling in cells expressing functional wild-type p53, whereas in cells expressing mutant or non-functional p53 DDX3 inhibits activation of the extrinsic apoptotic pathway to reduce caspase activation