Gene interactions and pathways from curated databases and text-mining

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PAK1 — RUNX2

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: RUNX2 → PAK1 (increases, PAK1 Activity, RUNX2 Activity) Qiao et al., J Biol Chem 2004*
    Evidence: The expression of GST·Pak1-(83–149) in EC inhibited basal (control) RUNX2 DNA binding activity relative to empty vector (Fig. 7A). # GST PAK1 is dominant-negative