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ARHGEF2 — PAK1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: PAK1 — ARHGEF2 (physical association, affinity chromatography technology) Zenke et al., J Biol Chem 2004*
• IRef Biogrid Interaction: PAK1 — ARHGEF2 (direct interaction, pull down) Zenke et al., J Biol Chem 2004*
• IRef Hprd Interaction: PAK1 — ARHGEF2 (in vitro) Zenke et al., J Biol Chem 2004*

Text-mined interactions from Literome

Zenke et al., J Biol Chem 2004 : We identify GEF-H1 as a binding target and substrate for p21 activated kinase 1 (PAK1) , an effector of Rac and Cdc42 GTPases, using an affinity based screen and localize a PAK1 phosphorylation site to the inhibitory carboxyl-terminal region of GEF-H1
Aslan et al., Am J Physiol Cell Physiol 2013 : Platelet activation by thrombin triggered the PAK dependent phosphorylation of GIT1, GEFH1 , and other PAK effectors, including LIMK1 and Merlin