◀ Back to IL4
CSF1 — IL4
Text-mined interactions from Literome
Nasu et al., Mol Hum Reprod 2001
:
It is suggested that
IL-4 secreted by the maternal decidual tissue as well as by the developing embryo may
stimulate the production of IL-6, IL-8, MCP-1, and
M-CSF by ESC
Piccinni et al., J Reprod Immunol 2001
(Abortion, Spontaneous) :
In addition, T cell production of Leukemia Inhibitory Factor (LIF) and
macrophage stimulating factor (M-CSF) , which are essential for embryo implantation and development, are
up-regulated by
IL-4 and progesterone
Frei et al., J Neuroimmunol 1992
:
Here we report that in addition to GM-CSF, murine astrocytes also produce
macrophage (M)-CSF upon
stimulation with tumor necrosis factor alpha,
interleukin-1 and lipopolysaccharides
Sierra-Filardi et al., Immunobiology 2010
(Melanoma...) :
M1-polarizing cytokines ( GM-CSF, IFNgamma ) inhibited, while
IL-4 enhanced , the
M-CSF-driven HO-1 expression
Broxmeyer et al., J Immunol 1988
:
Use of specific CSF antibodies suggested that rhu
IL-4 was
enhancing the release of G-CSF and
CSF-1 from monocytes and the release of GM-CSF and possibly G-CSF from PHA stimulated T lymphocytes
Riancho et al., J Endocrinol Invest 1995
:
IL-4 also
stimulated M-CSF expression by MC3T3 cells, both at the RNA and bioactivity levels
Gibbons et al., Lymphokine Cytokine Res 1994
:
Interleukin-4 enhances murine bone marrow macrophage
M-CSF receptor expression by a posttranscriptional mechanism
Welham et al., J Biol Chem 1994
:
The presence of
IL-4 neither diminished nor
enhanced the activation of p44erk-1 and p42erk-2 by
colony stimulating factor-1 , Steel factor, or 12-O-tetradecanoylphorbol-13-acetate
Riancho et al., Biochem Biophys Res Commun 1993
(Bone Resorption) :
Likewise, although
IL-4 may
stimulate M-CSF expression, its inhibitory effect on osteoclast recruitment was not prevented by anti-M-CSF antibodies, suggesting that it was not mediated by M-CSF
Galy et al., Lymphokine Cytokine Res 1993
:
IL-4 , which has been shown to partially modulate the IL-1 induced GM-CSF in TEC,
had no effect on constitutive or induced
M-CSF levels
Gruber et al., J Immunol 1994
:
Both
IL-4 and IL-10 strongly
inhibited M-CSF secretion by anti-CD45/IL-1 beta induced monocytes that was accompanied by decreased M-CSF message levels ...
IL-4 and IL-10
repressed M-CSF gene transcription but did not affect M-CSF message half-life
Hamilton et al., J Leukoc Biol 1993
:
We demonstrate with elutriation purified human monocytes that, in contrast to lipopolysaccharide, recombinant human
CSF-1 does not
induce secretion of prostaglandin E2,
interleukin-6 (IL-6), IL-1 beta, or tumor necrosis factor alpha, as measured by immunoassay ; however, increased urokinase-type plasminogen activator ( u-PA ) activity in cell lysates and mRNA was observed
Dupuis et al., Biochim Biophys Acta 1996
:
While GM-CSF ( 10 ng/ml ) and
interleukin-1 ( 10 U/ml )
stimulated M-CSF production from monocyte derived macrophages, PAF did not
Akagawa et al., Blood 1996
:
Rather, IFN-gamma antagonized the effect of IL-4 and suppressed the DC and MGC formation
induced by GM-CSF +
IL-4 and
M-CSF + IL-4, respectively