Gene interactions and pathways from curated databases and text-mining

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CSF1 — IL4

Text-mined interactions from Literome

Nasu et al., Mol Hum Reprod 2001 : It is suggested that IL-4 secreted by the maternal decidual tissue as well as by the developing embryo may stimulate the production of IL-6, IL-8, MCP-1, and M-CSF by ESC
Piccinni et al., J Reprod Immunol 2001 (Abortion, Spontaneous) : In addition, T cell production of Leukemia Inhibitory Factor (LIF) and macrophage stimulating factor (M-CSF) , which are essential for embryo implantation and development, are up-regulated by IL-4 and progesterone
Frei et al., J Neuroimmunol 1992 : Here we report that in addition to GM-CSF, murine astrocytes also produce macrophage (M)-CSF upon stimulation with tumor necrosis factor alpha, interleukin-1 and lipopolysaccharides
Sierra-Filardi et al., Immunobiology 2010 (Melanoma...) : M1-polarizing cytokines ( GM-CSF, IFNgamma ) inhibited, while IL-4 enhanced , the M-CSF-driven HO-1 expression
Broxmeyer et al., J Immunol 1988 : Use of specific CSF antibodies suggested that rhu IL-4 was enhancing the release of G-CSF and CSF-1 from monocytes and the release of GM-CSF and possibly G-CSF from PHA stimulated T lymphocytes
Riancho et al., J Endocrinol Invest 1995 : IL-4 also stimulated M-CSF expression by MC3T3 cells, both at the RNA and bioactivity levels
Gibbons et al., Lymphokine Cytokine Res 1994 : Interleukin-4 enhances murine bone marrow macrophage M-CSF receptor expression by a posttranscriptional mechanism
Welham et al., J Biol Chem 1994 : The presence of IL-4 neither diminished nor enhanced the activation of p44erk-1 and p42erk-2 by colony stimulating factor-1 , Steel factor, or 12-O-tetradecanoylphorbol-13-acetate
Riancho et al., Biochem Biophys Res Commun 1993 (Bone Resorption) : Likewise, although IL-4 may stimulate M-CSF expression, its inhibitory effect on osteoclast recruitment was not prevented by anti-M-CSF antibodies, suggesting that it was not mediated by M-CSF
Galy et al., Lymphokine Cytokine Res 1993 : IL-4 , which has been shown to partially modulate the IL-1 induced GM-CSF in TEC, had no effect on constitutive or induced M-CSF levels
Gruber et al., J Immunol 1994 : Both IL-4 and IL-10 strongly inhibited M-CSF secretion by anti-CD45/IL-1 beta induced monocytes that was accompanied by decreased M-CSF message levels ... IL-4 and IL-10 repressed M-CSF gene transcription but did not affect M-CSF message half-life
Hamilton et al., J Leukoc Biol 1993 : We demonstrate with elutriation purified human monocytes that, in contrast to lipopolysaccharide, recombinant human CSF-1 does not induce secretion of prostaglandin E2, interleukin-6 (IL-6), IL-1 beta, or tumor necrosis factor alpha, as measured by immunoassay ; however, increased urokinase-type plasminogen activator ( u-PA ) activity in cell lysates and mRNA was observed
Dupuis et al., Biochim Biophys Acta 1996 : While GM-CSF ( 10 ng/ml ) and interleukin-1 ( 10 U/ml ) stimulated M-CSF production from monocyte derived macrophages, PAF did not
Akagawa et al., Blood 1996 : Rather, IFN-gamma antagonized the effect of IL-4 and suppressed the DC and MGC formation induced by GM-CSF + IL-4 and M-CSF + IL-4, respectively