Gene interactions and pathways from curated databases and text-mining

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EGFR — S100A2

Text-mined interactions from Literome

Matsubara et al., Cancer Sci 2005 (Adenocarcinoma...) : Finally, we used oligonucleotide array analyses and identified potential S100A2 and S100A4 target genes involved in cancer progression : S100A2 induced RUNX3 and REPRIMO ; S100A4 induced EZRIN, RUNX1 and WISP1 ; S100A2 repressed EGFR , NFKB2 and RELA2 ; and S100A4 repressed ANXA10 and IL1RN
Lee et al., Gene Ther 2012 (Carcinoma, Non-Small-Cell Lung...) : EGF stimulated EGFR phosphorylation induced S100A2 expression and further activated E1A expression of Ad/SA, which was restored by EGFR signal inhibition in a concentration dependent manner in non-small-cell lung carcinoma ( NSCLC )